This issue of EFMD Global Focus calls for a fundamental transformation in business education to address complex global issues. As the world confronts challenges like climate change and social inequality, business schools are urged to reimagine their purpose and methods. Experts advocate for a shift from profit-focused teaching to fostering long-term thinking and innovation. This requires a complete rethinking of curricula, teaching approaches, and the core mission of business schools. Emphasis is placed on experiential learning and AI integration to bridge the gap between theory and practice, preparing students for real-world complexities. Faculty roles are evolving from content experts to learning facilitators and mentors, reflecting the changing needs of students and the business world. The focus is shifting beyond sustainability to regenerative business practices and ecosystem thinking, with climate change education now seen as essential, not optional, in core business curricula.